Saturday, 10 September 2016

The Smoothie Recipe Book: 150 Smoothie Recipes Including Smoothies for Weight Loss and Smoothies for Good Health

The Smoothie Recipe Book: 150 Smoothie Recipes Including Smoothies for Weight Loss and Smoothies for Good Health
This book has been brilliant for me and my husband, as we do tend to sometimes skip meals - especially breakfast and lunch when we are in a hurry trying to sort the young children out.

The recipes in this book are generally speaking really very tasty, and although they are 'healthy' they don't taste insipid or lack taste. Many of them are a brilliant way of getting your fruit and veg portions in.

The chapters are:
* Breakfast Smoothies
* Smoothies that Nourish your Brain
* Alkalizing Smoothies - Protect your Bones and Kidneys
* Anti-aging Smoothies
* Anti-Oxidant Smoothies
* Cleansing Smoothies
* Diabetic Smoothies
* Digestive Health Smoothies
* High-Energy Smoothies
* Green Smoothie Recipies
* Healthful Skin Recipes
* Kid-Friendly Smoothies
* Low-Fat Smoothies
* Protein Smoothies
* Weight-Loss Smoothies

I have to be honest, I haven't taken much notice of what the smoothies I've made are 'for' in terms of the chapter titles, although my mother in law has enjoyed some of the diabetic ones. But they are generally speaking pretty delicious.

Recommended

Tuesday, 23 August 2016

Review Wool Book

Review Wool Book
I am a long time science fiction reader and have read many wonderful stories that are based on science, technology, engineering and math. A few years ago I purchased a Kindle and it has opened up opportunities for me to read more with less effort and at less expense. I now have over two hundred science fiction books listed in my archives. Four days ago, I purchased the Wool Omnibus Edition by Hugh Howey. I finished it about an hour ago. This is the first review that I have ever been inspired to write about any book.

Some reviewers say that they cannot put a book down, once they get started into it. I have not understood this compulsion until last night, for the first time I had a hard time sleeping. I stopped reading sometime after midnight at a point in the book that left me anxious about the main character and was unwilling to disturb my wife by turning the light on or getting out of bed to pick up where I had left off. It takes a powerful piece of work to make me worry over what I know is fiction.

One small note to other authors that might be reading this review, part of what makes Wool a joy to read is the lack of grammatical and spelling errors of so many of the self published books. It is an extreme annoyance and distraction to me to read sentences in a book that I must stop, and reread substituting words that I think the author meant to understand the idea being communicated. Please take the time, your time or the time of others, to critically review your writing and fix these sentences that act as stumbling blocks for the reader on the journey you want to share with them. I and suspect many other readers would be willing to pay more for a book without grammatical and spelling errors.

I suspect this collection of a continuing story is going to become a classic. For many years now I have read and reread Foundation by Isaac Asimov and Dune by Frank Herbert along with other classics. This omnibus has the same deep commitment to the development of the characters and their feelings as they are caught up in a series of events that shape their future in an uplifting way from darker times. It is not complicated by a large cast of characters, like some series feel is necessary, but the few characters it does have are intertwined with one another and others in their society in a common journey through their lives.

I would highly recommend this to others, because I am sure that I will be rereading this story again and again.

Wednesday, 20 July 2016

Lewin's CELLS

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Lewin's CELLS La revue

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The ideal text for students in advanced cell biology courses, Lewin’s CELLS, Third Edition continues to offer a comprehensive, rigorous overview of the structure, organization, growth, regulation, movements, and interactions of cells, with an emphasis on eukaryotic cells. The text provides students with a solid grounding in the concepts and mechanisms underlying cell structure and function, and will leave them with a firm foundation in cell biology as well as a “big picture” view of the world of the cell. Revised and updated to reflect the most recent research in cell biology, Lewin’s CELLS, Third Edition includes expanded chapters on Nuclear Structure and Transport, Chromatin and Chromosomes, Apoptosis, Principles of Cell Signaling, The Extracellular Matrix and Cell Adhesion, Plant Cell Biology, and more. All-new design features and a chapter-by-chapter emphasis on key concepts enhance pedagogy and emphasize retention and application of new skills..


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Friday, 15 July 2016

Mitochondria

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Mitochondria Description

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"This volume inspires. It certainly will be much appreciated by cell biologists all over the world."
Quarterly Review of Biology, March 2009

This book is the eagerly awaited second edition of the best-selling Mitochondria, a book widely acknowledged as the first modern, truly comprehensive authored work on the important, scientifically fundamental topic of the cellular organelles known as mitochondria.

This new edition brings readers completely up to date on the many significant findings that have occurred in the eight years since the book was first published. As in that seminal first edition, the second edition tackles the biochemistry, genetics, and pathology of mitochondria in different organisms. The new edition provides thorough updates of all literature concerning this vital organelle, its functions, ongoing research surrounding it, and its importance vis-à-vis a broad range of issues in cellular and molecular biology. The book includes detailed descriptions of current and developing technologies around mitochondrial research and discovery, and highlights subjects that are growing, such as the use of proteomics.

This book is an invaluable resource for all geneticists, biologists, and educators in life sciences. It is also of interest for advanced students in genetics and molecular biology.

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Monday, 11 July 2016

Ap Biology Crash Course ( REA Test Preps )

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REA's AP Biology Crash Course is perfect for the last-minute studier or any AP student who wants a quick refresher on the course. /Fully updated to reflect the changes in the exam format, our easy-to-read test prep gives students a crash course in the major ideas, theories, and concepts in Biology. Written by an AP Biology teacher, the targeted review chapters focus only on the important topics tested on the exam including molecules and cells, heredity and evolution, organisms and population, and more. /The author provides key strategies for building point scores when answering the multiple-choice and open-ended questions. After reviewing the book, students can take a full-length practice exam online. With our Crash Course, students can study the material faster, learn the crucial facts, and boost their AP score all in less time..


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Tuesday, 5 July 2016

On Conscience (Bioethics & Culture)

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On Conscience (Bioethics & Culture) La revue

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Prepared and co-published by the National Catholic Bioethics Center in Philadelphia, this book is a combination of two lengthy essays written by Cardinal Ratzinger and delivered in talks when he was head of the Congregation for the Doctrine of the Faith. Both talks deal with the importance of conscience and its exercise in particular circumstances.

Ratzinger's reflections show that contemporary debates over the nature of conscience have deep historical and philosophical roots. He says that a person is bound to act in accord with his conscience, but he makes it clear that there must be reliable, proven sources for the judgment of conscience in moral issues, other than the subjective reflections of each individual.

The always unique and profound insights that the new Pope Benedict XVI brings to perennial problems reminds the reader of his strong warning before the recent Papal conclave of the great dangers today of the "dictatorship of relativism."

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Monday, 4 July 2016

Stop Working & Start Thinking

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Stop Working & Start Thinking La revue

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With the spectacular developments in technology accompanying and aiding scientific research over the past few decades, postgraduate students are often encouraged to focus more on generating data than to utilize their most sophisticated piece of equipment: their mind.
Stop Working & Start Thinking, Second Edition aims to encourage young researchers to think more clearly about their experiments, from experimental design to data interpretation. This new edition builds on the success of the first edition, with new material throughout and a new chapter on measurement interpretation, including an examination of cryptic assumptions.
This book is essential reading for postgraduates who wish to put the mastery back into their M.Sc. and the philosophy back into their PhDs..


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Sunday, 3 July 2016

Mind Wars: Brain Science and the Military in the 21st Century

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Mind Wars: Brain Science and the Military in the 21st Century La revue

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“One of the most important thinkers describes the literally mind-boggling possibilities that modern brain science could present for national security.” —LAWRENCE J. KORB, former US Assistant Secretary of Defense

“Fascinating and frightening.” —Bulletin of the Atomic Scientists

The first book of its kind, Mind Wars covers the ethical dilemmas and bizarre history of cutting-edge technology and neuroscience developed for military applications. As the author discusses the innovative Defense Advanced Research Projects Agency (DARPA) and the role of the intelligence community and countless university science departments in preparing the military and intelligence services for the twenty-first century, he also charts the future of national security.

Fully updated and revised, this edition features new material on deep brain stimulation, neuro hormones, and enhanced interrogation. With in-depth discussions of “psyops” mind control experiments, drugs that erase both fear and the need to sleep, microchip brain implants and advanced prosthetics, supersoldiers and robot armies, Mind Wars may read like science fiction or the latest conspiracy thriller, but its subjects are very real and changing the course of modern warfare.

Jonathan D. Moreno has been a senior staff member for three presidential advisory commissions and has served on a number of Pentagon advisory committees. He is an ethics professor at the University of Pennsylvania and the editor-in-chief of the Center for American Progress’ online magazine Science Progress.


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Tuesday, 21 June 2016

Junqueira's Basic Histology: Text and Atlas, 12th Edition

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Junqueira's Basic Histology: Text and Atlas, 12th Edition Info

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The most authoritative histology text available -- now in full-color

A Doody's Core Title ESSENTIAL PURCHASE for 2011!

For more than three decades, Junqueira's Basic Histology has been unmatched in its ability to explain the function of cell and tissue structure in the human body. Updated to reflect the latest research in the field, and enhanced with more than 1,000 illustrations, most in full-color, the 12th Edition is the most comprehensive and modern approach to understanding medical histology available anywhere.

Features:

  • NEW full-color micrographs that comprise a complete atlas of tissue sections highlight the important features of every tissue and organ in the human body.
  • New full-color, easy-to-understand drawings provide just the right level of detail necessary to clarify the text and make learning easier
  • A valuable introductory chapter on laboratory methods used for the study of tissues, including the most important types of microscopy
  • A logical organization that features chapters focusing on the cytoplasmic and nuclear compartment of the cell, the four basic tissues that form the organs, and each organ system
  • Expanded legends that accompany each figure emphasize important points and eliminate the need to jump from image to text
  • Medical applications explain the clinical relevance of each topic
  • Complete coverage of every tissue of the body
  • CD-ROM with all the images from the text

Visit www.LangeTextbooks.com to access valuable resources and study aids!

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The Shark's Paintbrush: Biomimicry and How Nature is Inspiring Innovation

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The Shark's Paintbrush: Biomimicry and How Nature is Inspiring Innovation Info

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Why does the bumblebee have better aerodynamics than a 747? What structural design is shared by a tornado and a blood vessel?

Since the Industrial Revolution, manufacturers have built things by a process known as “heat, beat, and treat.” They use enormous amounts of energy to heat raw material, shape it with heavy machinery, and maintain its design, strength, and durability with toxic chemicals. Now, in a world of depleted natural resources, entrepreneurs and scientists are turning to nature to inspire future products that are more energy- and cost-efficient. Biomimicry, the science of employing nature to advance sustainable technology, is arguably one of the hottest new business concepts. At the center of this growing movement has been award-winning inventor and biomimetic entrepreneur Jay Harman.

In The Shark's Paintbrush, Harman introduces us to pioneering engineers in a wide array of businesses who are uncovering and copying nature’s hidden marvels. He shows business leaders and aspiring entrepreneurs how we can reconcile creating more powerful, lucrative technologies with maximizing sustainability. He injects a whole new vocabulary and way of thinking into the business sphere that speaks to both small start-ups and corporate giants.
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Saturday, 11 June 2016

Introduction to Biometrics

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Introduction to Biometrics La revue

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Biometric recognition, or simply biometrics, is the science of establishing the identity of a person based on physical or behavioral attributes.  It is a rapidly evolving field with applications ranging from securely accessing one’s computer to gaining entry into a country. While the deployment of large-scale biometric systems in both commercial and government applications has increased the public awareness of this technology, "Introduction to Biometrics" is the first textbook to introduce the fundamentals of Biometrics to undergraduate/graduate students. The three commonly used modalities in the biometrics field, namely, fingerprint, face, and iris are covered in detail in this book. Few other modalities like hand geometry, ear, and gait are also discussed briefly along with advanced topics such as multibiometric systems and security of biometric systems. Exercises for each chapter will be available on the book website to help students gain a better understanding of the topics and obtain practical experience in designing computer programs for biometric applications. These can be found at: http://www.csee.wvu.edu/~ross/BiometricsTextBook/.

Designed for undergraduate and graduate students in computer science and electrical engineering, "Introduction to Biometrics" is also suitable for researchers and biometric and computer security professionals.

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Thursday, 9 June 2016

Essential Cell Biology

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Essential Cell Biology La revue

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Essential Cell Biology 4th edition is a good resource for students in an introductory and regular cell biology course..


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Saturday, 4 June 2016

Seeds of Deception & GMO Trilogy (Book & DVD Bundle)

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Seeds of Deception & GMO Trilogy (Book & DVD Bundle) Description

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Now Jeffrey M. Smith's best-selling book is paired with a new DVD and CD set that shows how genetically modified organisms (GMOs) put our health and environment at risk. This set will impact consumer perceptions and buying habits.

DVD 1: Unnatural Selection

This stunning, award-winning documentary by Bertram Verhaag and Gabriele Kröber reveals harsh consequences of genetic engineering on three continents. Vandana Shiva, Andrew Kimbrell, Percy Schmeiser and others, describe uncontrollable, self-replicating GM contamination, failed crops, farmer suicides, and new GM animals that threaten natural populations.

"Best Film," (CineEco, Portugal), "Best Long Production," (IEFF, Brazil), and "Best Journalistic Achievement," (IEFF, Germany).

"Meticulously researched, excellently photographed" -Ökomedia

 DVD 2: Hidden Dangers in Kids' Meals: Genetically Engineered Foods

Shocking research results, inadequate regulations and warnings from eminent scientists explain why GM foods are dangerous and should be removed from kids' meals. The dramatic story of how student behavior in a Wisconsin school was transformed with a healthy diet provides added motivation to make a change. It features Jeffrey Smith and more than a dozen scientists and experts. 

Audio CD: You're Eating WHAT?

Jeffrey Smith's riveting one-hour talk. 

Seeds of Deception

This is the top-rated, best selling book in the world on GM foods. Smith exposes the serious health dangers of genetically modified foods and the corporate cover-up. A fast-paced thriller of industry manipulation and political collusion, combined with lucid descriptions of genetic engineering and guidance on how to protect yourself and your family.

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Think-A-Lot-Tots: The Neuron: Science Books for Babies, Toddlers, and Kids

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Think-A-Lot-Tots: The Neuron: Science Books for Babies, Toddlers, and Kids Info

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How does our body move? How do we smile, wave hello, or stomp in puddles? It is all thanks to the brain's special helper: The Neuron. Dive into this educational picture book with your baby, toddler, or young child and discover the answers to their science and biology questions about moving and how we do it. This colorful and educational picture book will help build your child's vocabulary and kickstart early learning. Curious kids, budding scientists, and future doctors, nurses, and medical professionals are sure to become captivated by the neuron as they learn all about its different parts as well as how it helps the brain deliver messages to our body. There is no concept too abstract or advanced for tots that think a lot!.


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Sunday, 29 May 2016

Cell and Molecular Biology, Problems Book and Study Guide: Concepts and Experiments

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Balances coverage of the concepts of cell and molecular biology, using examples of experimentation to support those concepts. As experimental techniques become more diverse and complex, it is increasingly necessary to identify individual studies that have a broad impact on our understanding of cell biology. This text describes in detail some of the key experimental findings, along with the original data and figures..


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Friday, 27 May 2016

The Politics of Life Itself: Biomedicine, Power, and Subjectivity in the Twenty-First Century (In-Formation)

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The Politics of Life Itself: Biomedicine, Power, and Subjectivity in the Twenty-First Century (In-Formation) Description

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For centuries, medicine aimed to treat abnormalities. But today normality itself is open to medical modification. Equipped with a new molecular understanding of bodies and minds, and new techniques for manipulating basic life processes at the level of molecules, cells, and genes, medicine now seeks to manage human vital processes. The Politics of Life Itself offers a much-needed examination of recent developments in the life sciences and biomedicine that have led to the widespread politicization of medicine, human life, and biotechnology.


Avoiding the hype of popular science and the pessimism of most social science, Nikolas Rose analyzes contemporary molecular biopolitics, examining developments in genomics, neuroscience, pharmacology, and psychopharmacology and the ways they have affected racial politics, crime control, and psychiatry. Rose analyzes the transformation of biomedicine from the practice of healing to the government of life; the new emphasis on treating disease susceptibilities rather than disease; the shift in our understanding of the patient; the emergence of new forms of medical activism; the rise of biocapital; and the mutations in biopower. He concludes that these developments have profound consequences for who we think we are, and who we want to be.

For centuries, medicine aimed to treat abnormalities. But today normality itself is open to medical modification. Equipped with a new molecular understanding of bodies and minds, and new techniques for manipulating basic life processes at the level of molecules, cells, and genes, medicine now seeks to manage human vital processes. The Politics of Life Itself offers a much-needed examination of recent developments in the life sciences and biomedicine that have led to the widespread politicization of medicine, human life, and biotechnology.


Avoiding the hype of popular science and the pessimism of most social science, Nikolas Rose analyzes contemporary molecular biopolitics, examining developments in genomics, neuroscience, pharmacology, and psychopharmacology and the ways they have affected racial politics, crime control, and psychiatry. Rose analyzes the transformation of biomedicine from the practice of healing to the government of life; the new emphasis on treating disease susceptibilities rather than disease; the shift in our understanding of the patient; the emergence of new forms of medical activism; the rise of biocapital; and the mutations in biopower. He concludes that these developments have profound consequences for who we think we are, and who we want to be.

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Tuesday, 24 May 2016

Tissue Culture Techniques: An Introduction

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Tissue Culture Techniques: An Introduction Description

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ACKNOWLEDGMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl II INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . I STERILITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Aseptic Technique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Physical manipulations • Use of the sterile cabinet (hood) Sterilization Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Heat • Radiation • Toxic gas • Filtration • Antibiotics Quality Control of Sterilization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 Routine labeling Suggested Readings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Exercises . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 vi CONTENTS ROUTINE CELL CULTURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Feeding Schedules and Media Components . . . . . . . . . . . . . . . . . . . . 29 General properties of media and salt solutions • water as a reagent· Establishingfeeding schedules Subcultivation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 Solutions and methods for adherent cells • Common enzyme solutions • Inoculating (seeding) the cultures Cell Enumeration and Cell Viability . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Hemocytometer • Particle counter • Cell viability Putting Routine Methods to Work . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 Normal cell growth characteristics Detecting and Disposing of Contamination . . . . . . . . . . . . . . . . . . . . 66 Bacteria and fUngi • Fungi • Mycoplasma • Viruses • Dealing with contamination Troubleshooting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 Inadequate cell growth • Recurrent contamination • When to call your vendor Safety . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Biological hazards • Chemical hazards Suggested Readings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 Problem Set . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 Exercises . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 EXPERIMENTS IN CULTURE . . . . . . . . . . . . . . . . . . . . . . . . . . 91 II Alterations of the Media . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 Serum • Treatments of serum • Plasma-derived serum • Serum-free and low-protein media Substrata. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Coatingplasticware with solutions • Alterations with polymers • Using cells to coat the plasticware • Culturing cells on microcarriers Altering the Environment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 Temperature changes • Gaseous changes Problem Set . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 Exercises . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 CONTENTS vii PRIMARY CELL CULTURE. . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 Isolation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 Dissection • Enzymatic dissociation methods • Nonenzymatic isolation • Purification of cell suspensions • Consideringyield and survival Chatacterization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ..


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Sunday, 22 May 2016

Protein NMR Spectroscopy: Principles and Practice

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Protein NMR Spectroscopy combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning with simple theoretical models and experimental techniques, Protein NMR Spectroscopy develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.

Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. The second edition includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.

Protein NMR Spectroscopy is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or who wish to understand the latest developments in this field.

· Provides an understanding of the theoretical principles important for biological NMR spectroscopy
· Demonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experiments
· Allows for the capability of designing effective experimental protocols for investigations of protein structures and dynamics
· Includes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods.


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Saturday, 21 May 2016

BIOTECH.:SCI.F/NEW MILLENIUM-L

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BIOTECH.:SCI.F/NEW MILLENIUM-L.


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Thursday, 19 May 2016

The Antidote: Inside the World of New Pharma

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In this timely and much praised book, Barry Werth draws upon inside reporting that spans more than two decades. He provides a groundbreaking close-up of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits.

In 1989, the charismatic Joshua Boger left Merck, then America’s most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company’s tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex’s bold endurance and eventual success.

The 5 billion-a-year pharmaceutical business is America’s toughest and one of its most profitable. It’s riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world’s most regulated industry, matched only by nuclear power.

Werth captures the full scope of Vertex’s twenty-five-year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades..


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Monday, 16 May 2016

Dynamic Systems Biology Modeling and Simulation

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Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels.  The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author’s own modeling efforts, publications and teaching over half a century.  Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical.  The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility.  The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications.



  • Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics; PLUS …….
  • The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of “math modeling” with life sciences.
  • Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization.
  • Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models.
  • A full set of PowerPoint slides are available from the author for teaching from his textbook.  He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course.

Importantly, the slides are editable, so they can be readily adapted to a lecturer’s personal style and course content needs.  The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content.

The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: joed@cs.ucla.edu

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Wednesday, 4 May 2016

Introduction to Genetics: A Molecular Approach

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Genetics today is inexorably focused on DNA. The theme of Introduction to Genetics: A Molecular Approach is therefore the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). This progression reflects both the basic logic of life and the way in which modern biological research is structured. The molecular approach is particularly suitable for the large number of students for whom genetics is a part of a broader program in biology, biochemistry, the biomedical sciences, and biotechnology.

Introduction to Genetics presents the basic facts and concepts with enough depth of knowledge to stimulate students to move on to more advanced aspects of the subject. The book is divided into three parts. Part 1 examines the function of the gene as a unit of biological information. Part 2 studies the role of the gene as a unit of inheritance. And Part 3 explores some of the areas of research that are responsible for the high profile that genetics has in our modern world, from agriculture and industry to medicine and forensics, and the ethical challenges that genetic knowledge imparts.

Introduction to Genetics is available for purchase as an e-book in its entirety or as individual chapters, and as a 1-year or 6-month rental.

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Monday, 2 May 2016

Life at the Speed of Light: From the Double Helix to the Dawn of Digital Life

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The renowned scientist and author of A Life Decoded examines the creation of life in the new field of synthetic genomics

In 2010, scientists led by J. Craig Venter became the first to successfully create “synthetic life”—putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution.

In Life at the Speed of Light, Venter presents a fascinating and authoritative study of this emerging field from the inside—detailing its origins, current challenges and controversies, and projected effects on our lives. This scientific frontier provides an opportunity to ponder anew the age-old question “What is life?” and examine what we really mean by “playing God.” Life at the Speed of Light is a landmark work, written by a visionary at the dawn of a new era of biological engineering..


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Thursday, 28 April 2016

Physiological Basis of Aging and Geriatrics, Fourth Edition

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Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields.

New updated information includes:





  • emphasis on emerging technologies and recent advances in biology and bioengineering that allow greater and longer independence of the elderly

  • recent therapeutic developments in key diseases such as Alzheimer's, osteopenia, osteoporosis, high cholesterol, diabetes, gastritis, sexual impotence, and using transgenic animals as models of aging

  • evaluation of the latest knowledge on the roles of oxidants and antioxidants, and correlates them with other aging-based theories

  • expanded discussion of nutrition and physical exercise

  • chapters on gene and stem cell interventions related to the aging process

  • updated tables to reflect current trends, new research data, and up-to-date statistical information
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Tuesday, 26 April 2016

The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care

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The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care Description

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Until very recently, if you were to ask most doctors, they would tell you there were only two kinds of medicine: the quack kind, and the evidence-based kind. The former is baseless, and the latter based on the best information human effort could buy, with carefully controlled double-blind trials, hundreds of patients, and clear indicators of success.Well, Eric Topol isn't most doctors, and he suggests you entertain the notion of a third kind of medicine, one that will make the evidence-based state-of-the-art stuff look scarcely better than an alchemist trying to animate a homunculus in a jar. It turns out plenty of new medicines-although tested with what seem like large trials-actually end up revealing most of their problems only once they get out in the real world, with millions of people with all kinds of conditions mixing them with everything in the pharmacopeia. The unexpected interactions of drugs, patients, and diseases can be devastating. And the clear indicators of success often turn out to be minimal, often as small as one fewer person dying out of a hundred (or even a thousand), and often at exorbitant cost. How can we avoid these dangerous interactions and side-effects? How can we predict which person out of a hundred will be helped by a new drug, and which fatally harmed? And how can we avoid having to need costly drugs in the first place?It sure isn't by doing another four hundred-person trial. As Topol argues in The Creative Destruction of Medicine, it's by bringing the era of big data to the clinic, laboratory, and hospital, with wearable sensors, smartphone apps, and whole-genome scans providing the raw materials for a revolution. Combining all the data those tools can provide will give us a complete and continuously updated picture of every patient, changing everything from the treatment of disease, to the prolonging of health, to the development of new treatments. As revolutionary as the past twenty years in personal technology and medicine have been-remember phones the sizes of bricks that only made calls, or when the most advanced "genotyping" we could do involved discerning blood types and Rh-factors?-Topol makes it clear that we haven't seen a thing yet. With an optimism matched only by a realism gained through twenty-five years in a tough job, Topol proves the ideal guide to the medicine of the future-medicine he himself is deeply involved in creating..


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Saturday, 23 April 2016

Phylogenomics: A Primer

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Phylogenomics: A Primer is for advanced undergraduate and graduate biology students studying molecular biology, comparative biology, evolution, genomics, and biodiversity. It
explores the origins of organic life on the planet, examines the use of scientific databases to understand the function of proteins within organisms, and provides insight into the interpretation of linear sequence information in the context of organismal change. This book explains the essential concepts underlying the storage and manipulation of genomics level data, construction of phylogenetic trees, population genetics, natural selection, the
tree of life, DNA barcoding, and metagenomics. The inclusion of problem-solving exercises in each chapter provides students with a solid grasp of the important molecular and evolutionary questions facing modern biologists as well as the tools needed to answer them. Online exercises are also available to assist students in working with the programs and databases used to analyze phylogenomic data.

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