Saturday, 31 October 2015

PCR (THE BASICS (Garland Science))

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PCR (THE BASICS (Garland Science)) La revue

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A thoroughly updated version of the successful first edition with a new chapter on Real-Time PCR, more prokaryotic applications, and more detail in the complex mutagenesis sections. Information on PCR applications in genomics and proteomics have been expanded and integrated throughout the text. There is also advice on available products and specific pointers to the most appropriate methods. As with the first edition, this will be an ideal practical introduction and invaluable guide to PCR and its applications..


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Thursday, 29 October 2015

Field Methods in Marine Science: From Measurements to Models

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Field Methods in Marine Science: From Measurements to Models is an authoritative guide of the methods most appropriate for field research within the marine sciences, from experimental design to data analysis. Written for upper-level undergraduate and graduate students as well as early-career researchers, this textbook also serves as an accessible introduction to the concepts and practice of modeling marine system dynamics. This textbook trains the next generation of field scientists to move beyond the classic methods of data collection and statistical analysis to contemporary methods of numerical modeling; to pursue the assimilation and synthesis of information, not the mere recording of data. Boxes and side bars highlight important questions, interesting facts, relevant examples, and research techniques that supplement the text.  Students and researchers alike will find the thorough appendices useful as a way of expanding comprehension of fundamental concepts. .


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Fundamentals of Light Microscopy and Electronic Imaging

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Fundamentals of Light Microscopy and Electronic Imaging Description

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Over the last decade, advances in science and technology have profoundly changed the face of light microscopy. Research scientists need to learn new skills in order to use a modern research microscope–skills such as how to align microscope optics and perform image processing. Fundamentals of Light Microscopy and Electronic Imaging explores the basics of microscope design and use. The comprehensive material discusses the optical principles involved in diffraction and image formation in the light microscope, the basic modes of light microscopy, the components of modern electronic imaging systems, and the image processing operations necessary to acquire and prepare an image.

Written in a practical, accessible style, Fundamentals of Light Microscopy and Electronic Imaging reviews such topics as:

  • Illuminators, filters, and isolation of specific wavelengths
  • Phase contrast and differential interference contrast
  • Properties of polarized light and polarization microscopy
  • Fluorescence and confocal laser scanning microscopy
  • Digital CCD microscopy and image processing

Each chapter includes practical demonstrations and exercises along with a discussion of the relevant material. In addition, a thorough glossary assists with complex terminology and an appendix contains lists of materials, procedures for specimen preparation, and answers to questions.

An essential resource for both, experienced and novice microscopists..


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Tuesday, 27 October 2015

Junk DNA: A Journey Through the Dark Matter of the Genome

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Junk DNA: A Journey Through the Dark Matter of the Genome La revue

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For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98% of the human genome were dismissed as “junk,” sequences that serve no purpose. Yet recently researchers have discovered variations and modulations in this junk DNA that underwrite a number of intractable diseases. This knowledge has led to innovative research and treatment approaches that may finally control these conditions.

Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word “gene” and has engendered a bitter battle over whether or not this genomic “nonsense” is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey’s book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field.
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Bacteria in Biology, Biotechnology and Medicine

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Bacteria in Biology, Biotechnology and Medicine Description

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Bacteria in Biology, Biotechnology and Medicine is a broadly based textbook of pure and applied bacteriology. Written in clear language, the up-to-date text gives readers access to new ideas and developments in the current literature. The book is intended primarily for undergraduates and postgraduates in biology, biotechnology, medicine, veterinary science, pharmacology, microbiology, food science, environmental science and agriculture; no prior knowledge of bacteria is assumed.

The sixth edition has been extensively updated; much of the text is new, or re-written, and there are many new references. Over 70 genera of bacteria, listed alphabetically, are described in the Appendix. Cross-references and a detailed index, maximise the accessibility of data.

Reviews of previous editions:

"….a useful survey of the subject for students contemplating specialization."
—Nature

"Singleton assumes the reader has no prior knowledge of DNA and gene expression, and does an extraordinary job of explaining things from scratch."
—Quarterly Review of Biology

"….recommended to undergraduates and those seeking clear explanations of basic concepts of bacteriology."
—Journal of Medical Microbiology

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Monday, 26 October 2015

Protein Purification: Principles and Practice (Springer Advanced Texts in Chemistry)

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Protein Purification: Principles and Practice (Springer Advanced Texts in Chemistry) Info

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New textbooks at all levels of chemistry appear with great regularity. Some fields such as basic biochemistry, organic re action mechanisms, and chemical thermodynamics are weil represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research that is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instruc­ tive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In so me cases the availability of texts in active research areas should help stimulate the creation of new courses..


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Wednesday, 21 October 2015

Bioengineering: A Conceptual Approach (Food Engineering Series)

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Bioengineering: A Conceptual Approach (Food Engineering Series) La revue

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This book explores critical principles and new concepts in bioengineering, integrating the biological, physical and chemical laws and principles that provide a foundation for the field. Both biological and engineering perspectives are included, with key topics such as the physical-chemical properties of cells, tissues and organs; principles of molecules; composition and interplay in physiological scenarios; and the complex physiological functions of heart, neuronal cells, muscle cells and tissues. Chapters evaluate the emerging fields of nanotechnology, drug delivery concepts, biomaterials, and regenerative therapy. The leading individuals and events are introduced along with their critical research. Bioengineering: A Conceptual Approach is a valuable resource for professionals or researchers interested in understanding the central elements of bioengineering. Advanced-level students in biomedical engineering and computer science will also find this book valuable as a secondary textbook or reference..


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Tuesday, 20 October 2015

Molecular Medicine: An Introduction

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Molecular Medicine: An Introduction Description

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Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine..


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Friday, 16 October 2015

Biology of Aging

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Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease.  Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material..


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Thursday, 15 October 2015

Navigating Metabolism

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Navigating Metabolism Info

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Complex metabolic pathway diagrams are a hallmark of many biochemistry textbooks. But what do they tell us about disease, physiology, cell signaling, aging, immunity, and gene expression? In a refreshing approach to the subject of metabolism, Navigating Metabolism provides a conceptual framework for navigating these pathways, showing how cells generate energy and synthesize cellular constituents and then further relating metabolic reactions to molecular, genetic, and signaling underpinnings. These principles are supported by copious illustrations that clearly represent metabolic reactions, making them accessible and relating them to the ways in which cells respond to stimuli to produce specific biological outcomes. The last few decades have brought metabolism to the fore, with new results suggesting that it plays a regulatory role in signaling pathways and gene expression. Viewing metabolism in this new light provides hope that it may be an avenue for providing effective prevention and targeted treatment for many of the diseases that plague us--cardiovascular, inflammatory disease, diabetes, and cancer. Authored by Navdeep Chandel, a leading investigator in the field, Navigating Metabolism is the perfect introduction to this modern view of metabolic studies.
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Practical Statistics for Environmental and Biological Scientists

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Practical Statistics for Environmental and Biological Scientists Description

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All students and researchers in environmental and biological sciences require statistical methods at some stage of their work. Many have a preconception that statistics are difficult and unpleasant and find that the textbooks available are difficult to understand.

Practical Statistics for Environmental and Biological Scientists provides a concise, user-friendly, non-technical introduction to statistics. The book covers planning and designing an experiment, how to analyse and present data, and the limitations and assumptions of each statistical method. The text does not refer to a specific computer package but descriptions of how to carry out the tests and interpret the results are based on the approaches used by most of the commonly used packages, e.g. Excel, MINITAB and SPSS. Formulae are kept to a minimum and relevant examples are included throughout the text.

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Wednesday, 14 October 2015

Bioethics: A Primer for Christians: Revised

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In the face of rapid advances in medical research and treatment, bioethics has become a serious social concern. Originally published in 1996 and later chosen by World magazine as one of the top 100 books of the twentieth century, Gilbert Meilaenders Bioethics covers a wide range of pressing bioethical issues and offers discerning guidance on how Christians ought to think about them.In admirably clear language Meilaender discusses abortion, assisted reproduction, genetic advance and prenatal screening, care for the dying and euthanasia, human experimentation, and more. This new edition of his Bioethics features updated information throughout, a fuller discussion of human embryos — including stem cell research — and a thorough rewrite of the chapter on organ donation.In the face of rapid advances in medical research and treatment, bioethics has become a serious social concern. Originally published in 1996 and later chosen by World magazine as one of the top 100 books of the twentieth century, Gilbert Meilaenders Bioethics covers a wide range of pressing bioethical issues and offers discerning guidance on how Christians ought to think about them.In admirably clear language Meilaender discusses abortion, assisted reproduction, genetic advance and prenatal screening, care for the dying and euthanasia, human experimentation, and more. This new edition of his Bioethics features updated information throughout, a fuller discussion of human embryos — including stem cell research — and a thorough rewrite of the chapter on organ donation..


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Sunday, 11 October 2015

The Wisdom of Your Cells: How Your Beliefs Control Your Biology

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The Wisdom of Your Cells: How Your Beliefs Control Your Biology Description

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When was the last time that learning about a scientific breakthrough left you feeling invigorated, optimistic and empowered to take charge of your life? In the tradition of Carl Sagan, Rachel Carson and Stephen Hawking, a new voice has emerged with the unique gift of translating cutting edge science into clear, accessible language-Dr. Bruce Lipton. With The Wisdom of Your Cells, this internationally recognized authority on cellular biology takes listeners on an in-depth exploration into the microscopic world, where new discoveries and research are revolutionizing the way we understand life, evolution, and consciousness. On this full-length audio course, Dr. Lipton shares his lucid and startling insights about the building blocks of life, and how each one of our cells has far greater innate intelligence than we once believed..


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Saturday, 10 October 2015

Nanotechnology: Understanding Small Systems, Third Edition (Mechanical and Aerospace Engineering Series)

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Nanotechnology: Understanding Small Systems, Third Edition (Mechanical and Aerospace Engineering Series) Info

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An Accessible, Scientifically Rigorous Presentation That Helps Your Students Learn the Real Stuff

Winner of a CHOICE Outstanding Academic Book Award 2011
"… takes the revolutionary concepts and techniques that have traditionally been fodder for graduate study and makes them accessible for all. … outstanding introduction to the broad field of nanotechnology provides a solid foundation for further study. Highly recommended."
N.M. Fahrenkopf, University at Albany, CHOICE Magazine 2011

Give your students the thorough grounding they need in nanotechnology. A rigorous yet accessible treatment of one of the world’s fastest growing fields, Nanotechnology: Understanding Small Systems, Third Edition provides an accessible introduction without sacrificing rigorous scientific details. This approach makes the subject matter accessible to students from a variety of disciplines. Building on the foundation set by the first two bestselling editions, this third edition maintains the features that made previous editions popular with students and professors alike.

See What’s New in the Third Edition:

  • Updated coverage of the eight main facets of nanotechnology
  • Expanded treatment of health/environmental ramifications of nanomaterials
  • Comparison of macroscale systems to those at the nanoscale, showing how scale phenomena affects behavior
  • New chapter on nanomedicine
  • New problems, examples, and an exhaustive nanotech glossary

Filled with real-world examples and original illustrations, the presentation makes the material fun and engaging. The systems-based approach gives students the tools to create systems with unique functions and characteristics. Fitting neatly between popular science books and high-level treatises, the book works from the ground up to provide a gateway into an exciting and rapidly evolving area of science.

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Friday, 9 October 2015

Microcosm: E. coli and the New Science of Life

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Microcosm: E. coli and the New Science of Life Info

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A Best Book of the YearSeed Magazine Granta Magazine The Plain-DealerIn this fascinating and utterly engaging book, Carl Zimmer traces E. coli's pivotal role in the history of biology, from the discovery of DNA to the latest advances in biotechnology. He reveals the many surprising and alarming parallels between E. coli's life and our own. And he describes how E. coli changes in real time, revealing billions of years of history encoded within its genome. E. coli is also the most engineered species on Earth, and as scientists retool this microbe to produce life-saving drugs and clean fuel, they are discovering just how far the definition of life can be stretched.


From the Trade Paperback edition.A Best Book of the YearSeed Magazine Granta Magazine The Plain-DealerIn this fascinating and utterly engaging book, Carl Zimmer traces E. coli's pivotal role in the history of biology, from the discovery of DNA to the latest advances in biotechnology. He reveals the many surprising and alarming parallels between E. coli's life and our own. And he describes how E. coli changes in real time, revealing billions of years of history encoded within its genome. E. coli is also the most engineered species on Earth, and as scientists retool this microbe to produce life-saving drugs and clean fuel, they are discovering just how far the definition of life can be stretched.


From the Trade Paperback edition..


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Thursday, 8 October 2015

Plant Biotechnology: Comprehensive Biotechnology Second Supplement (Comprehensive Biotechnology Supplement Series)

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Plant Biotechnology: Comprehensive Biotechnology Second Supplement (Comprehensive Biotechnology Supplement Series) Description

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Today it is generally accepted that one of the key areas of biotechnology for the next century will be in plant-based biotechnology. Biotechnology has created new opportunities for plant scientists, with important applications to agriculture and forestry. This reference text is divided into five sections for ease of presentation. The first section focuses on the structure, composition and functionality of plant cells and genes with particular emphasis on the cellular and molecular biology of plants and cultured cells. Section two is concerned with the direct exploitation of cell cultures for the production of useful substances. The third section deals with regeneration and propagation systems. The fourth section considers the increasingly central area of genetic manipulation of plant cell systems. The last section is on specific applications in plant biotechnology. This reference work is a survey of these various facets of plant biotechnology. The individual chapters and the follow-up literature cited allow an easy access to the various subject areas and will, hopefully, stimulate interest in these rapidly moving and exciting fields of research..


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Tuesday, 6 October 2015

Principles of Microbiological Troubleshooting in the Industrial Food Processing Environment (Food Microbiology and Food Safety)

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Principles of Microbiological Troubleshooting in the Industrial Food Processing Environment (Food Microbiology and Food Safety) La revue

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Written with the in-plant food safety/quality assurance professional in mind, this reference offers proven approaches and suggestions for finding sources of microbiological contamination of industrially produced products..


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Cell and Molecular Biology, Binder Ready Version: Concepts and Experiments

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Cell and Molecular Biology, Binder Ready Version: Concepts and Experiments La revue

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This text is an unbound, three hole punched version.

Designed for courses in Cell Biology offered at the Sophomore/Junior level, Karp's Cell and Molecular Biology: Concepts and Experiments, Binder Ready Version, 8th Edition continues to be the best book in the market at connecting key concepts to the experiments that reveal how we know what we know in the world of Cell Biology. This classic text explores core concepts in considerable depth, often adding experimental detail. It is written in an inviting style and at mid-length, to assist students in managing the plethora of details encountered in the Cell Biology course.  In this edition, two new co-authors take the helm and help to expand upon the hallmark strengths of the book, update and integrate text and media in a useful way, improving the student learning experience..


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Monday, 5 October 2015

Field Methods in Marine Science: From Measurements to Models

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Field Methods in Marine Science: From Measurements to Models

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Field Methods in Marine Science: From Measurements to Models is an authoritative guide of the methods most appropriate for field research within the marine sciences, from experimental design to data analysis. Written for upper-level undergraduate and graduate students as well as early-career researchers, this textbook also serves as an accessible introduction to the concepts and practice of modeling marine system dynamics. This textbook trains the next generation of field scientists to move beyond the classic methods of data collection and statistical analysis to contemporary methods of numerical modeling; to pursue the assimilation and synthesis of information, not the mere recording of data. Boxes and side bars highlight important questions, interesting facts, relevant examples, and research techniques that supplement the text. Students and researchers alike will find the thorough appendices useful as a way of expanding comprehension of fundamental concepts..


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Sunday, 4 October 2015

The Double Helix: A Personal Account of the Discovery of the Structure of DNA

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The Double Helix: A Personal Account of the Discovery of the Structure of DNA

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The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work."Science seldom proceeds in the straightforward logical manner imagined by outsiders," writes James Watson in The Double Helix, his account of his codiscovery (along with Francis Crick) of the structure of DNA. Watson and Crick won Nobel Prizes for their work, and their names are memorized by biology students around the world. But as in all of history, the real story behind the deceptively simple outcome was messy, intense, and sometimes truly hilarious. To preserve the "real" story for the world, James Watson attempted to record his first impressions as soon after the events of 1951-1953 as possible, with all their unpleasant realities and "spirit of adventure" intact.

Watson holds nothing back when revealing the petty sniping and backbiting among his colleagues, while acknowledging that he himself was a willing participant in the melodrama. In particular, Watson reveals his mixed feelings about his famous colleague in discovery, Francis Crick, who many thought of as an arrogant man who talked too much, and whose brilliance was appreciated by few. This is the joy of The Double Helix--instead of a chronicle of stainless-steel heroes toiling away in their sparkling labs, Watson's chronicle gives readers an idea of what living science is like, warts and all. The Double Helix is a startling window into the scientific method, full of insight and wit, and packed with the kind of science anecdotes that are told and retold in the halls of universities and laboratories everywhere. It's the stuff of legends. --Therese LittletonThe classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work..


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Glia (Cold Spring Harbor Perspectives in Biology)

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The majority of cells in the nervous system are glia. Long thought of as passive bystanders, glial cells are increasingly being appreciated for their active roles in nourishing, supporting, and protecting the neuronal cells that relay electrical signals through the nervous system.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the development of the major classes of glial cells-astrocytes, oligodendrocytes, Schwann cells, and microglia-and their roles in normal physiology and disease. The contributors describe how glia help establish and refine synaptic connections, maintain the metabolic and ionic milieu of nerve cells, myelinate axons, modulate nerve signal propagation, and contribute to the blood-brain barrier. The biological characteristics of glial cells in vertebrate and invertebrate model systems, including those of Drosophila, Caenorhabditis elegans, and zebrafish, are also covered.

The authors also discuss the roles of glia in repair and regeneration, as well as in cancer and neurodegenerative diseases (e.g., Alzheimer's). This volume is therefore a valuable reference for all neurobiologists and biomedical scientists wishing to understand these diverse and dynamic cells.
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The Antidote: Inside the World of New Pharma

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In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.

The 5-billion-a-year pharmaceutical business is America's toughest and one of its most profitable. It is riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power.

Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades.

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Thursday, 1 October 2015

Designs on Nature: Science and Democracy in Europe and the United States

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Biology and politics have converged today across much of the industrialized world. Debates about genetically modified organisms, cloning, stem cells, animal patenting, and new reproductive technologies crowd media headlines and policy agendas. Less noticed, but no less important, are the rifts that have appeared among leading Western nations about the right way to govern innovation in genetics and biotechnology. These significant differences in law and policy, and in ethical analysis, may in a globalizing world act as obstacles to free trade, scientific inquiry, and shared understandings of human dignity.

In this magisterial look at some twenty-five years of scientific and social development, Sheila Jasanoff compares the politics and policy of the life sciences in Britain, Germany, the United States, and in the European Union as a whole. She shows how public and private actors in each setting evaluated new manifestations of biotechnology and tried to reassure themselves about their safety.

Three main themes emerge. First, core concepts of democratic theory, such as citizenship, deliberation, and accountability, cannot be understood satisfactorily without taking on board the politics of science and technology. Second, in all three countries, policies for the life sciences have been incorporated into "nation-building" projects that seek to reimagine what the nation stands for. Third, political culture influences democratic politics, and it works through the institutionalized ways in which citizens understand and evaluate public knowledge. These three aspects of contemporary politics, Jasanoff argues, help account not only for policy divergences but also for the perceived legitimacy of state actions.

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