Monday, 31 August 2015

No Small Matter: Science on the Nanoscale

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No Small Matter: Science on the Nanoscale La revue

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A small revolution is remaking the world. The only problem is, we can’t see it. This book uses dazzling images and evocative descriptions to reveal the virtually invisible realities and possibilities of nanoscience. An introduction to the science and technology of small things, No Small Matter explains science on the nanoscale.
Authors Felice C. Frankel and George M. Whitesides offer an overview of recent scientific advances that have given us our ever-shrinking microtechnology—for instance, an information processor connected by wires only 1,000 atoms wide. They describe the new methods used to study nanostructures, suggest ways of understanding their often bizarre behavior, and outline their uses in technology. This book explains the various means of making nanostructures and speculates about their importance for critical developments in information processing, computation, biomedicine, and other areas.
No Small Matter considers both the benefits and the risks of nano/microtechnology—from the potential of quantum computers and single-molecule genomic sequencers to the concerns about self-replicating nanosystems. By making the practical and probable realities of nanoscience as comprehensible and clear as possible, the book provides a unique vision of work at the very boundaries of modern science..


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Power, Sex, Suicide: Mitochondria and the Meaning of Life

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Power, Sex, Suicide: Mitochondria and the Meaning of Life Info

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If it weren't for mitochondria, scientists argue, we'd all still be single-celled bacteria. Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.
In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.
Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures..


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Tissue Engineering: Engineering Principles for the Design of Replacement Organs and Tissues

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Tissue Engineering: Engineering Principles for the Design of Replacement Organs and Tissues Info

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Tissue or organ transplantation are among the few options available for patients with excessive skin loss, heart or liver failure, and many common ailments, and the demand for replacement tissue greatly exceeds the supply, even before one considers the serious constraints of immunological tissue type matching to avoid immune rejection. Tissue engineering promises to help sidestep constraints on availability and overcome the scientific challenges, with huge medical benefits. This book lays out the principles of tissue engineering. It will be a useful reference work for those associated with this field and as a textbook for specialized courses in the subject. It is a companion volume to Saltzman's OUP book on drug delivery.Tissue or organ transplantation are among the few options available for patients with excessive skin loss, heart or liver failure, and many common ailments, and the demand for replacement tissue greatly exceeds the supply, even before one considers the serious constraints of immunological tissue type matching to avoid immune rejection. Tissue engineering promises to help sidestep constraints on availability and overcome the scientific challenges, with huge medical benefits. This book lays out the principles of tissue engineering. It will be a useful reference work for those associated with this field and as a textbook for specialized courses in the subject. It is a companion volume to Saltzman's OUP book on drug delivery..


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Life at the Speed of Light: From the Double Helix to the Dawn of Digital Life

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Life at the Speed of Light: From the Double Helix to the Dawn of Digital Life Description

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“Venter instills awe for biology as it is, and as it might become in our hands.” —Publishers Weekly

On May 20, 2010, headlines around the world announced one of the most extraordinary accomplishments in modern science: the creation of the world’s first synthetic lifeform. In Life at the Speed of Light, scientist J. Craig Venter, best known for sequencing the human genome, shares the dramatic account of how he led a team of researchers in this pioneering effort in synthetic genomics—and how that work will have a profound impact on our existence in the years to come. This is a fascinating and authoritative study that provides readers an opportunity to ponder afresh the age-old question “What is life?” at the dawn of a new era of biological engineering..


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Saturday, 29 August 2015

Biotechnology

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Biotechnology Description

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Biotechnology, Second Edition approaches modern biotechnology from a molecular basis, which has grown out of increasing biochemical understanding of genetics and physiology. Using straightforward, less-technical jargon, Clark and Pazdernik introduce each chapter with basic concepts that develop into more specific and detailed applications. This up-to-date text covers a wide realm of topics including forensics, bioethics, and nanobiotechnology using colorful illustrations and concise applications. In addition, the book integrates recent, relevant primary research articles for each chapter, which are presented on an accompanying website. The articles demonstrate key concepts or applications of the concepts presented in the chapter, which allows the reader to see how the foundational knowledge in this textbook bridges into primary research. This book helps readers understand what molecular biotechnology actually is as a scientific discipline, how research in this area is conducted, and how this technology may impact the future.



  • Up-to-date text focuses on modern biotechnology with a molecular foundation
  • Includes clear, color illustrations of key topics and concept
  • Features clearly written without overly technical jargon or complicated examples
  • Provides a comprehensive supplements package with an easy-to-use study guide, full primary research articles that demonstrate how research is conducted, and instructor-only resources
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Friday, 28 August 2015

Babies by Design: The Ethics of Genetic Choice

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Babies by Design: The Ethics of Genetic Choice Description

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We stand on the brink of unprecedented growth in our ability to understand and change the human genome. New reproductive technologies now enable parents to select some genetic traits for their children, and soon it will be possible to begin to shape ourselves as a species. Despite the loud cries of alarm that such a prospect inspires, Ronald Green argues that we will, and we should, undertake the direction of our own evolution. A leader in the bioethics community, Green offers a scientifically and ethically informed view of human genetic self-modification and the possibilities it opens up for a better future. Fears of a terrible Brave New World or a new eugenics movement are overblown, he maintains, and in the more likely future, genetic modifications may improve parents' ability to enhance children's lives and may even promote social justice. The author outlines the new capabilities of genomic science, addresses urgent questions of safety that genetic interventions pose, and explores questions of parenting and justice. He also examines the religious implications of gene modification.
Babies by design are assuredly in the future, Green concludes, and by making responsible choices as we enter that future, we can incorporate gene technology in a new age of human adventure.We stand on the brink of unprecedented growth in our ability to understand and change the human genome. New reproductive technologies now enable parents to select some genetic traits for their children, and soon it will be possible to begin to shape ourselves as a species. Despite the loud cries of alarm that such a prospect inspires, Ronald Green argues that we will, and we should, undertake the direction of our own evolution. A leader in the bioethics community, Green offers a scientifically and ethically informed view of human genetic self-modification and the possibilities it opens up for a better future. Fears of a terrible Brave New World or a new eugenics movement are overblown, he maintains, and in the more likely future, genetic modifications may improve parents' ability to enhance children's lives and may even promote social justice. The author outlines the new capabilities of genomic science, addresses urgent questions of safety that genetic interventions pose, and explores questions of parenting and justice. He also examines the religious implications of gene modification.
Babies by design are assuredly in the future, Green concludes, and by making responsible choices as we enter that future, we can incorporate gene technology in a new age of human adventure..


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Thursday, 27 August 2015

GMO Sapiens:The Life-Changing Science of Designer Babies

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Genetically modified organisms (GMOs) including plants and the foods made from them, are a hot topic of debate today, but soon related technology could go much further and literally change what it means to be human. Scientists are on the verge of being able to create people who are GMOs.

Should they do it? Could we become a healthier and 'better' species or might eugenics go viral leading to a real, new world of genetic dystopia? GMO Sapiens tackles such questions by taking a fresh look at the cutting-edge biotech discoveries that have made genetically modified people possible.

Bioengineering, genomics, synthetic biology, and stem cells are changing sci-fi into reality before our eyes. This book will capture your imagination with its clear, approachable writing style. It will draw you into the fascinating discussion of the life-changing science of human genetic modification.

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Wednesday, 26 August 2015

Monoclonal Antibodies: Principles and Practice

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Monoclonal Antibodies: Principles and Practice La revue

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Monoclonal Antibodies now have applications in virtually all areas of biology and medicine, and much of the world's biotechnology industry has its foundations in the exploitation of this technology.
The Third Edition of this well established book meets the needs of both newcomers to the area and experienced researchers, by providing an integrated treatment of both the production and application of monoclonal antibodies. As in previous editions, detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies are given, along with descriptions of their use in antigen characterization, affinity chromatography and immunofluorescence. The present volume has been comprehensively updated to cover recent rapid advances, particularly with respect to the applications of molecular biology, the use of antibodies in closing and heterologous expression of genes, immunohistology and phage display libraries. Since the previous edition, there has been a growing trend towards the replacement of procedures using radioactive isotopes, and the current edition incorporates these newer technologies.
The text is oriented towards problems solving, and makes it easy to adapt each procedure to individual needs. Extensive cross-referencing, a glossary and a comprehensive index make this book an essential reference.
This book will be vital both for laboratories already producing or using monoclonal antibodies, and for workers in many disciplines who are contemplating their use.

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* Provides an integrated treatment of both the production and application of monoclonals in cell biology, biochemistry, and immunology.
* Gives detailed and critical accounts of the theory, production, purification, storage, and relabelling of monoclonals, and their use in antigen characterization, affinity chromorography, and immunofluroscence.
* Comprehensively updated to cover the rapid advances that have occurred since the publication of the Second Edition.
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Dynamic Systems Biology Modeling and Simulation

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Dynamic Systems Biology Modeling and Simulation Info

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Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels.  The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author’s own modeling efforts, publications and teaching over half a century.  Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical.  The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility.  The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications.

  • Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics; PLUS …….
  • The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of “math modeling” with life sciences.
  • Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization.
  • Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models.
  • A full set of PowerPoint slides are available from the author for teaching from his textbook.  He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course.

Importantly, the slides are editable, so they can be readily adapted to a lecturer’s personal style and course content needs.  The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content.

The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: joed@cs.ucla.edu

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Tuesday, 25 August 2015

Cell Biology: A Short Course

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Cell Biology: A Short Course Description

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This text tells the story of cells as the units of life in a colorful and student-friendly manner, taking an "essentials only" approach. By using the successful model of previously published "Short Courses," this text succeeds in conveying the key points without overburdening the reader with secondary information. The authors (all active researchers and educators) skillfully present concepts by illustrating them with clear diagrams and examples from current research. Special boxed sections focus on the importance of cell biology in medicine and industry today. This text is completely updated from the successful "Cell Biology, A Short Course, 2e," includes new chapters and now has a supporting website with tests and animations for students and power point slides and supplemental material for instructors: http://www.wileyshortcourse.com/cellbiology/default.asp.


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Introduction to Protein Structure

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Introduction to Protein Structure Info

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Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions..


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Monday, 24 August 2015

Principles of Microbiological Troubleshooting in the Industrial Food Processing Environment (Food Microbiology and Food Safety)

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Principles of Microbiological Troubleshooting in the Industrial Food Processing Environment (Food Microbiology and Food Safety) Description

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Written with the in-plant food safety/quality assurance professional in mind, this reference offers proven approaches and suggestions for finding sources of microbiological contamination of industrially produced products..


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Introduction to Kinesiology: Studying Physical Activity, Third Edition

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Introduction to Kinesiology: Studying Physical Activity, Third Edition Info

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Introduction to Kinesiology: Studying Physical Activity, Third Edition, explains the evolving discipline of kinesiology, demonstrating how its many subject areas integrate into a unified body of knowledge. This all-inclusive approach gives students a solid background in the field and prepares them for further study and course work. Engaging and jargon-free, this outstanding text also introduces students to the available job prospects and areas of study and professional practice in kinesiology.

Introduction to Kinesiology, Third Edition, orients and prepares students for in-depth studies in their areas of interest. The broad scope of this text acknowledges students' diverse interests and aspirations in teaching and coaching, professional, and scholarly career tracks. Within the text, top kinesiologists expand discussion of physical activity beyond exercise, sport, or health-related activity in order to broaden conceptions of physical activity and the potential contributions of kinesiology.

The book is organized into three parts: Experiencing Kinesiology, Scholarly Study of Kinesiology, and Professional Practice in Kinesiology. Throughout the text, emphasis on the integration of experience, formal study, and professional practice seeks to balance the importance of these unique and interrelated dimensions of the discipline.

-Experiencing Kinesiology provides broad discussion of how physical activity experiences in sport, exercise, work, rehabilitation, and daily living contribute to the understanding of kinesiology. This section concentrates on how kinesiologists design and manipulate physical activity experiences. It also discusses the subjective aspects of physical activity, inviting students to consider various types of knowledge and understanding to be gleaned from the experience of physical activity.

-Scholarly Study of Kinesiology introduces students to the academic subdisciplines of kinesiology, including philosophy, history, and sociology of physical activity; motor behavior; sport and exercise psychology; and biomechanics and physiology of physical activity. Job descriptions of professionals in each subdiscipline educate students on academic careers available, and practical, real-world applications illustrate the importance of the subdiscipline and how it may relate or contribute to a variety of professional endeavors.

-Professional Practice in Kinesiology defines the responsibilities and requirements of professionals in health and fitness, therapeutic exercise, teaching, coaching, and sport management. Using a step-by-step process, students can determine whether their interest, talent, and motivation are appropriate for a career in kinesiology. Work setting analyses, educational qualifications, case studies, profiles of working professionals, and career advice provide additional information for career considerations.
Both new and returning contributors share their perspectives in fully updated chapters complemented by full-color photos and illustrations. Professional Profiles, interviews with kinesiology professionals found throughout the text, illustrate how knowledge of kinesiology subareas applies to professional practice. Chapter objectives help students keep the main ideas in mind as they read through the chapter, and chapter summaries can be found at the end of each chapter to reinforce ideas. Key points and sidebars supplement information in the text. Study questions at the end of each chapter help students focus on key areas of the text. Exercises and activities actively involve students in learning the material.

Introduction to Kinesiology, Third Edition, is also available as an e-book. The e-book is available at a reduced price and allows students to highlight, take notes, and easily access the online study guide features with direct links throughout the text. When purchased through the Human Kinetics site, access to the e-book is immediately granted when your order is received. The print book and e-book are also available as a package.

The third edition of Introduction to Kinesiology presents the discipline of kinesiology in a new and exciting way. Clearly organized and reader-friendly, this exemplary text portrays the variety, complexity, elegance, and importance of physical activity. With its full-color format and engaging writing style, the text will be a beneficial tool as it orients students to the discipline of kinesiology and its diverse professions.

Includes an online study guide!

To assist students using the text, Introduction to Kinesiology, Third Edition, has a companion online student study guide. Completely integrated with the text, the study guide allows students to experience content through multiple dimensions. Students will receive free access to the study guide with the purchase of a new text or e-book, or it may be purchased as a separate component. The online study guide offers students a variety of learning features:

-Interactive activities. Using a variety of multimedia experiences, these activities engage students in the material. Scenario-based audio and video activities demonstrate an aspect of kinesiology and then require students to complete an activity based on the demonstration and explanation. Other activities involve drag-and-drop, selecting from a menu, or responding with short answers to photos and scenarios presented.

-Study questions. These questions reinforce key material throughout the text and help students comprehend the concepts.

-Review of key points. The online review allows students to test themselves on the key points with the use of interactive activities. Students have the option of printing out the key points as a study aid after completing the activity.

-Activity feedback. Students receive targeted information to correct or reinforce their answers to activities.

-Web searches. Students can seek out specific information on the Internet and then provide their findings on forms that can be printed out and turned in to instructors.

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Saturday, 22 August 2015

The Physiology and Biochemistry of Prokaryotes

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The third edition of The Physiology and Biochemistry of Prokaryotes covers the basic principles of prokaryotic physiology, biochemistry, and cell behavior. It presents microbial metabolism in the context of the chemical and physical problems that cells must solve in order to grow.

Written in a clear, straightforward manner, the book provides a modern perspective on the diversity of microorganisms, and an updated account of the major aspects prokaryotes, such as cell structure, metabolism, developmental biology, environmental adaptation, biofilm formation, and cellular signaling pathways. It is organized according to topic rather than by organism, therefore helping students understand the general principles of physiology and metabolism. Each chapter ends with thought-provoking study questions, a summary, and an extensive list of references to outside research literature students may go to for more information and detailed explanations of material in the text.

The Physiology and Biochemistry of Prokaryotes, Third Edition, is ideal for advanced undergraduate and graduate courses on microbial physiology of bacterial metabolism. It can be used in conjunction with a laboratory manual, Microbial Physiology and Biochemistry Laboratory: A Quantitative Approach, by David White and George D. Hegeman.

Features of the Third Edition


·Includes New Material on: Cell Division, Cell-Cell Signaling, Cell Development, Biofilm Formation


·Contains boxed asides that cite interesting historical information about important discoveries and notable people in the field from the 19th Century to the 1960s.


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Cells, Tissues, and Disease

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Cells, Tissues, and Disease

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Cells, Tissues, and Disease Description

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Cells, Tissues, and Diseases is a highly readable introduction to the etiology, morphology, and mechanisms of disease. Chapters like "The Cell as Elementary Patient" and "How Cancer Kills" illustrate the authors' emphasis on clear, straightforward - though highly sophisticated - discussions of pathologic states. References ranging from fish markets to pate de fois gras reinforce the theme that disease can be seen in all walks of life, and serve to make the information relevant and interesting. Meticulously edited bibliographies provide both student and instructor a wealth of related sources..


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Friday, 21 August 2015

Cell Signalling

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Cell Signalling

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Cell Signalling Info

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Signalling within and between cells is an essential part of many biological processes, from the development of the body to the activity of our immune system.

Cell Signalling, Third Edition, presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems. Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms before examining how these components come together to create signalling pathways, which are so crucial to the survival of many living organisms. The text is enhanced by two-color artwork and 3-D protein models. A Companion Website provides resources for students and instructors.
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Thursday, 20 August 2015

Molecular Evolution: A Phylogenetic Approach

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Molecular Evolution: A Phylogenetic Approach

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Molecular Evolution: A Phylogenetic Approach Info

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The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals.

  • First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution.
  • Chapter summaries and annotated suggestions for further reading.
  • Worked examples facilitate understanding of some of the more complex issues.
  • Emphasis on clarity and accessibility.
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Principles of Neurobiology

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Principles of Neurobiology

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Principles of Neurobiology La revue

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Principles of Neurobiology presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, journal club suggestions, figures in PowerPoint, and a Question Bank for adopting instructors.

Principles of Neurobiology is additionally supported by the Garland Science Learning System. This homework platform is designed to evaluate and improve student performance and allows instructors to select assignments on specific topics and review the performance of the entire class, as well as individual students, via the instructor dashboard. Students receive immediate feedback on their mastery of the topics, and will be better prepared for lectures and classroom discussions. The user-friendly system provides a convenient way to engage students while assessing progress. Performance data can be used to tailor classroom discussion, activities, and lectures to address students’ needs precisely and efficiently. For more information and sample material, visit http://garlandscience.rocketmix.com/.

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Clinical Simulation

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Clinical Simulation Info

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Simulation facilities are invaluable for training in medicine and clinical education, biomedical engineering and life sciences. They allow the practice of prevention, containment, treatment, and procedure in a risk-free setting.

This book is a practical guide and reference to the latest technology, operations and opportunities presented by clinical simulation. It shows how to develop and make efficient use of resources, and provides hands-on information to those tasked with setting up and delivering simulation facilities for medical, clinical and related purposes, and the development and delivery of simulation-based education programs

• A step-by-step manual to developing successful simulation programs
• Shows how to design, construct, outfit and run simulation facilities for clinical education and research.
• The Residency Review Committee of the US Accreditation Council on Graduate Medical Education has begun requiring residency programs to have simulation as an integral part of their training programs..


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Wednesday, 19 August 2015

Signal Transduction: Principles, Pathways, and Processes

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Signal Transduction: Principles, Pathways, and Processes Info

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Cells must respond to a wide variety of signals. These include hormones, growth factors, morphogens, and environmental stress, as well as signals from internal regulators and checkpoints. A complex network of signal transduction pathways within the cell ensures that these signals are relayed to the correct molecular targets and that the cell responds appropriately.

This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. Taking a novel approach, it first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function.

The book is essential reading for students learning about signal transduction for the first time. It will also be a vital reference for all cell, molecular, and developmental biologists and pharmacologists, neurobiologists, and immunologists studying processes regulated by cell signaling.
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Tuesday, 18 August 2015

Biofuels Refining and Performance

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Biofuels Refining and Performance

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Biofuels Refining and Performance Info

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Learn about the ways to economically manufacture biofuels

Written by a team of international experts, Biofuels Refining and Performance describes the refining processes and issues involved in producing fuel derived from recently living organisms or their by-products. Each chapter offers detailed discussion of theory as well as the actual experimental procedure used to economically manufacture biofuels on a commercial scale..


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Monday, 17 August 2015

Medical Instrument Design and Development: From Requirements to Market Placements

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Medical Instrument Design and Development: From Requirements to Market Placements

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Medical Instrument Design and Development: From Requirements to Market Placements La revue

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This book explains all of the stages involved in developing medical devices; from concept to medical approval including system engineering, bioinstrumentation design, signal processing, electronics, software and ICT with Cloud and e-Health development. 

Medical Instrument Design and Development offers a comprehensive theoretical background with extensive use of diagrams, graphics and tables (around 400 throughout the book). The book explains how the theory is translated into industrial medical products using a market-sold Electrocardiograph disclosed in its design by the Gamma Cardio Soft manufacturer.

The sequence of the chapters reflects the product development lifecycle. Each chapter is focused on a specific University course and is divided into two sections: theory and implementation. The theory sections explain the main concepts and principles which remain valid across technological evolutions of medical instrumentation. The Implementation sections show how the theory is translated into a medical product.  The Electrocardiograph (ECG or EKG) is used as an example as it is a suitable device to explore to fully understand medical instrumentation since it is sufficiently simple but encompasses all the main areas involved in developing medical electronic equipment. 

Key Features:

  • Introduces a system-level approach to product design
  • Covers topics such as bioinstrumentation, signal processing, information theory, electronics, software, firmware, telemedicine, e-Health and medical device certification
  • Explains how to use theory to implement a market product (using ECG as an example)
  • Examines the design and applications of main medical instruments
  • Details the additional know-how required for product implementation: business context, system design, project management, intellectual property rights, product life cycle, etc.
  • Includes an accompanying website with the design of the certified ECG product (www.gammacardiosoft.it/book)
  • Discloses the details of a marketed ECG Product (from Gamma Cardio Soft)  compliant with the ANSI standard AAMI EC 11 under open licenses (GNU GPL, Creative Common)

This book is written for biomedical engineering courses (upper-level undergraduate and graduate students) and for engineers interested in medical instrumentation/device design with a comprehensive and interdisciplinary system perspective.

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Friday, 14 August 2015

The Antidote: Inside the World of New Pharma

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The Antidote: Inside the World of New Pharma Info

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In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success. The 5-billion-a-year pharmaceutical business is America's toughest and one of its most profitable. It is riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's twenty-five-year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades..


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Thursday, 13 August 2015

The Cell: A Molecular Approach, Sixth Edition

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The Cell: A Molecular Approach, Sixth Edition

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The Cell: A Molecular Approach, Sixth Edition Description

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Designed for use in shorter introductory cellular biology courses, The Cell presents current comprehensive science in a readable and cohesive text. The sixth edition retains the overall organization, themes, and special features that made the previous edition so popular, but has been updated throughout to reflect major advances in the field. The book will be supported by a companion website, which offers a wealth of study and review material as well as rich multimedia resources including: quizzes, animations of key concepts and processes, chapter summaries, interactive micrographs and a collection of video microscopy showing biological processes in action..


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Wednesday, 12 August 2015

The Neuron: Cell and Molecular Biology

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The Neuron: Cell and Molecular Biology

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The Neuron: Cell and Molecular Biology Description

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The third edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The first part of the book covers the properties of the many ion channels that shape the way a single neuron generates varied patterns of electrical activity, as well as the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter hormones at synaptic junctions between neurons. The second part covers the biochemical pathways that are linked to the action of neurotransmitters and can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning and memory..


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