Tuesday, 31 March 2015

The Path to the Double Helix: The Discovery of DNA (Dover Books on Biology)

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The Path to the Double Helix: The Discovery of DNA (Dover Books on Biology) Info

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The 1953 discovery by James Watson and Francis Crick of the molecular structure of DNA ranks among the most dramatic events in the history of science. In this lively, perceptive, and scholarly study, a noted historian of science provides the first in-depth account of this milestone's achievement.
Combining scientific and historical approaches, the narrative vividly recaptures the excitement of the conceptualization and evolution of ideas that led to the discovery of the genetic "secret of life." The story unfolds along several major lines: long-chain macromolecules; nucleic acids; bacterial transformations; the intellectual evolutions of physicists, chemists, and biologists; and the cross-pollination of scientific disciplines that unlocked the structural secrets of DNA. Francis Crick provides an illuminating Foreword for this abundantly illustrated and thought-provoking retelling of a great scientific detective story.
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Sunday, 29 March 2015

Awakenings,

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Awakenings, Info

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“Compulsively readable. . . . Dr. Sacks writes beautifully and with exceptional subtlety and penetration into both the state of mind of his patients and the nature of illness generally. . . . A brilliant and humane book.” ― A. Alvarez, The Observer Awakenings ― which inspired the major motion picture ― is the remarkable story of a group of patients who contracted sleeping-sickness during the great epidemic just after World War I. Frozen for decades in a trance-like state, these men and women were given up as hopeless until 1969, when Dr. Oliver Sacks gave them the then-new drug L-DOPA, which had an astonishing, explosive, “awakening” effect. Dr. Sacks recounts the moving case histories of his patients, their lives, and the extraordinary transformations that went with their reintroduction to a changed world. “[Sacks] opens to the reader doors of perception generally passed through only by those at the far borders of human experience.” ― The Boston Globe “One of the most beautifully composed and moving works of our time.” ― The Washington Post “A masterpiece.” ― W. H. AudenIt hardly seems fair that so many great doctors are also great writers. Perhaps it's qualities like sensitivity, craft, and dedication that keep physicians like Oliver Sacks in hospitals all day and at writing desks all night; if nothing else, these qualities shine in books like Awakenings. This powerful set of case histories rises above its pathological foundation to find new literary territory, a medical-spiritual synthesis equally stimulating for the mind and the soul. It's no wonder Hollywood producers chose to turn it into a feature film--anyone can see the universal human struggle against bondage and despair in these pages.

The sleeping-sickness epidemic of 1918 caused hundreds of survivors to slip into a bizarre rigid paralysis with similarities to advanced Parkinson's disease. These patients, only occasionally able to communicate or move, were nearly all institutionalized for life, their ranks increasing every now and then with similarly afflicted men and women. Sacks came to work at a long-term care facility shortly before the first exciting results with L-dopa and Parkinson's in the late 1960s; his patients soon embarked on dramatic, difficult recoveries from up to 50 years of torpor. He documents their spiritual and medical obstacles with great care to portray their individual personalities, long suppressed but finally released. Though many great doctors are also great writers, few can compare with Oliver Sacks for expressing the relation of medicine to the human spirit. --Rob Lightner.


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Carbohydrates: The Sweet Molecules of Life

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Carbohydrates: The Sweet Molecules of Life La revue

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This book is on carbohydrates-the essential molecules that give you energy. They are the building blocks of life. This book delivers up-to-date coverage on all aspects of carbohydrate chemistry. The molecules are sometimes sugars, i.e. "sweet," hence the subtitle "The Sweet Molecules of Life."

Carbohydrates first gives the "nuts and bolts" of carbohydrate chemistry, enabling the reader to appreciate the subsequent chapters on protecting groups and the reactions of monosaccharides. (The protecting groups do just that-they are put on the molecules as a temporary measure during one or more reactions to stop the wrong bit of the molecule being changed during that reaction.)

* Introduces the basic chemistry of carbohydrates
* Describes the concepts, protecting groups, and reactions of carbohydrates
* Includes all aspects of the synthesis of the glycosidic linkage
* Gives an introduction to glycobiology and vaccines
* Includes references to carbohydrate literature.


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Saturday, 28 March 2015

The Medical Device R&D Handbook, Second Edition

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The Medical Device R&D Handbook, Second Edition La revue

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Exploring the practical, entrepreneurial, and historical aspects of medical device development, this second edition of The Medical Device R&D Handbook provides a how-to guide for medical device product development. The book offers knowledge of practical skills such as prototyping, plastics selection, and catheter construction, allowing designers to apply these specialized techniques for greater innovation and time saving.

The author discusses the historical background of various technologies, helping readers understand how and why certain devices were developed. The text also contains interviews with leaders in the industry who offer their vast experience and insights on how to start and grow successful companies—both what works and what doesn’t work. This updated and expanded edition adds new information to help meet the challenges of the medical device industry, including strategic intellectual property management, operating room observation protocol, and the use of new technologies and new materials in device development.

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Molecular Medicine: An Introduction

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Molecular Medicine: An Introduction Info

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Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine..


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Friday, 27 March 2015

Apple Pie and Enchiladas: Latino Newcomers in the Rural Midwest

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Apple Pie and Enchiladas: Latino Newcomers in the Rural Midwest Description

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The sudden influx of significant numbers of Latinos to the rural Midwest stems from the recruitment of workers by food processing plants and small factories springing up in rural areas. Mostly they work at back-breaking jobs that local residents are not willing to take because of the low wages and few benefits. The region has become the scene of dramatic change involving major issues facing our country—the intertwining of ethnic differences, prejudice, and poverty; the social impact of a low-wage workforce resulting from corporate transformations; and public policy questions dealing with economic development, taxation, and welfare payments.

In this thorough multidisciplinary study, the authors explore both sides of this ethnic divide and provide the first volume to focus comprehensively on Latinos in the region by linking demographic and qualitative analysis to describe what brings Latinos to the area and how they are being accommodated in their new communities. The fact is that many Midwestern communities would be losing population and facing a dearth of workers if not for Latino newcomers. This finding adds another layer of social and economic complexity to the region's changing place in the global economy. The authors look at how Latinos fit into an already fractured social landscape with tensions among townspeople, farmers, and others. The authors also reveal the optimism that lies in the opposition of many Anglos to ethnic prejudice and racism.

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The Double Helix: A Personal Account of the Discovery of the Structure of DNA

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By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

With humility unspoiled by false modesty, Watson relates his and Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences: the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

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Thursday, 26 March 2015

From Computer to Brain: Foundations of Computational Neuroscience

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From Computer to Brain: Foundations of Computational Neuroscience Description

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Biology undergraduates, medical students and life-science graduate students often have limited mathematical skills. Similarly, physics, math and engineering students have little patience for the detailed facts that make up much of biological knowledge. Teaching computational neuroscience as an integrated discipline requires that both groups be brought forward onto common ground. This book does this by making ancillary material available in an appendix and providing basic explanations without becoming bogged down in unnecessary details. The book will be suitable for undergraduates and beginning graduate students taking a computational neuroscience course and also to anyone with an interest in the uses of the computer in modeling the nervous system..


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C. elegans: A Practical Approach (The Practical Approach Series)

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C. elegans: A Practical Approach (The Practical Approach Series) Info

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Caenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system. It has recently taken on new importance with the publication of the entire genome sequence in 1998. The first chapter gives all the basic information on C. elegans required to use it: it's natural history, anatomy, life cycle, development, and evolution. Information on how to obtain, grow, and maintain C. elegans for use as a model system is given in Chapter 4. Chapters 2 and 3 describe the genome project and show how to use genome sequence information by searching the database for homologues using different search methods and then how to analyse the search data. The next chapter gives the essential practical details of transformation and common uses for the technique. Chapter 6 covers reverse genetics and describes strategies for gene inactivation that are known to work in C elegans: epigenetic inactivation and mutational germ line inactivation. Chapter 7 is designed to help the user analyse phenotype by microscopy and includes Normaski, fluorescence, 4-dimensional, and electron microscopy. Techniques for studying the neurobiology of C. elegans are given in chapter 8. Chapter 9 describes the three commonly used approaches for studying gene expression and Chapter 10 deals with the common methods of molecular biology essential for gene characterization. C. elegans is not the ideal organism for biochemical studies, but chapter 11 describes several procedures for producing biochemically useful quantities of pure tissues. The final chapter is about conventional genetics and details the standard procedures for selfing and crossing; mutagenesis and mutant screening; characterization of mutants; gene mapping; temperature-shift experiments and mosCaenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system. It has recently taken on new importance with the publication of the entire genome sequence in 1998. The first chapter gives all the basic information on C. elegans required to use it: it's natural history, anatomy, life cycle, development, and evolution. Information on how to obtain, grow, and maintain C. elegans for use as a model system is given in Chapter 4. Chapters 2 and 3 describe the genome project and show how to use genome sequence information by searching the database for homologues using different search methods and then how to analyse the search data. The next chapter gives the essential practical details of transformation and common uses for the technique. Chapter 6 covers reverse genetics and describes strategies for gene inactivation that are known to work in C elegans: epigenetic inactivation and mutational germ line inactivation. Chapter 7 is designed to help the user analyse phenotype by microscopy and includes Normaski, fluorescence, 4-dimensional, and electron microscopy. Techniques for studying the neurobiology of C. elegans are given in chapter 8. Chapter 9 describes the three commonly used approaches for studying gene expression and Chapter 10 deals with the common methods of molecular biology essential for gene characterization. C. elegans is not the ideal organism for biochemical studies, but chapter 11 describes several procedures for producing biochemically useful quantities of pure tissues. The final chapter is about conventional genetics and details the standard procedures for selfing and crossing; mutagenesis and mutant screening; characterization of mutants; gene mapping; temperature-shift experiments and mos.


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Wednesday, 25 March 2015

Principles of Neurobiology

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Principles of Neurobiology Description

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Principles of Neurobiology presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, journal club suggestions, figures in PowerPoint, and a Question Bank for adopting instructors.

Principles of Neurobiology is additionally supported by the Garland Science Learning System. This homework platform is designed to evaluate and improve student performance and allows instructors to select assignments on specific topics and review the performance of the entire class, as well as individual students, via the instructor dashboard. Students receive immediate feedback on their mastery of the topics, and will be better prepared for lectures and classroom discussions. The user-friendly system provides a convenient way to engage students while assessing progress. Performance data can be used to tailor classroom discussion, activities, and lectures to address students’ needs precisely and efficiently. For more information and sample material, visit http://garlandscience.rocketmix.com/.

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Tuesday, 24 March 2015

Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods

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Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods La revue

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Eating genetically modified food is gambling with every bite.

The biotech industry's claim that genetically modified (GM) foods are safe is shattered in this groundbreaking book. Sixty-five health risks of the foods that Americans eat every day are presented in easy-to-read two-page spreads. The left page is designed for the quick scanning reader; it includes bullets, illustrations, and quotes. The right side offers fully referenced text, describing both research studies and theoretical risks. The second half of Genetic Roulette shows how safety assessments on GM crops are not competent to identify the health problems presented in the first half. It also exposes how industry research is rigged to avoid finding problems.

This book, prepared in with input by more than 30 scientists, is for anyone wanting to understand GM technology, to learn how to protect themselves, or to share their concerns with others. It is presented in the clear, accessible style that made Jeffrey Smith's Seeds of Deception the world's best-selling book on genetically engineered foods. As the world's most complete reference on the health risks of GM foods, Genetic Roulette is also ideal for schools and libraries..


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Dinoflagellates (Cell Biology)

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Dinoflagellates (Cell Biology) Info

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The book begins with a general introduction and a taxonomic description of the dinoflagellates both to acquaint those unfamiliar with this group of organisms and to set the tone for the rest of the volume. It then addresses the following topics: cell biology (cell cortex, nuclear structure, cell cycle and mitosis, sexual reproduction, cysts and unusual inclusions); biochemistry (physiology and biochemistry, blooms and toxins, and biorhythms); and genetics. In addition, a comprehensive chapter on cell culturing provides the reader with an understanding of the growth conditions and requirements of various dinoflagellates and a simple to follow listing of culture media, all expressed in similar units for ease of comparison. The volume closes with a chapter on evolution which evaluates many of the features of dinoflagellates discussed in the text in terms of evolutionary significance.
We hope that this treatise will be of use to research workers and students in the area of dinoflagellate biology and in other areas of biology in which dinoflagellates may be used as a model system for studying various biological problems..


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Monday, 23 March 2015

Prolyl Hydroxylase, Protein Disulfide Isomerase and Other Structurally Related Proteins

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Prolyl Hydroxylase, Protein Disulfide Isomerase and Other Structurally Related Proteins Info

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Addressing the folding of proteins to natural states as well as cotranslational and post translational modifications that effect function, this work analyzes the function of specific enzymes in the complex processes of protein conformation, assembly and stability. It highlights up-to-date advances made in creating accurate protein folding for protein stability, offering results in understanding disease pathology and the development of better drugs..


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Saturday, 21 March 2015

Biofuels Engineering Process Technology

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Biofuels Engineering Process Technology Description

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New Process Technology for Developing Low-Cost, Environmentally Safe Biofuels

Rising fuel prices have created a surge in the worldwide demand for biofuels made from plant and animal feedstocks. Filled with a wealth of illustrations, Biofuels Engineering Process Technology fully explains the concepts, systems, and technology now being used to produce biofuels on both an industrial and small scale.

Written by a team of leading biofuels experts, this lucid guide presents a complete introduction to biofuels and biorefining processes…state-of-the-art information on biofuels processed from fermentations of ethanol, hydrogen, microbial oils, and methane…new material on the production of biodiesel from plant and algal oils…and the use of microbial fuel cells to produce bioelectricity. Biofuels Engineering Process Technology takes readers step by step through:

  • The key concepts, systems, and technology of biofuels
  • A review of the basic concepts of fermentation pathways and kinetic modeling of bioreactors
  • Biofuels produced from fermentations of agricultural feedstocks and biomass-ethanol, hydrogen, microbial oils, and methane
  • Biodiesel fuels processed from the chemical conversion of microbial and plant oils
  • Bioelectricity produced from microbial fuel cells
  • The latest sustainable biorefinery concepts and methods

Inside This Cutting-Edge Biofuels Engineering Guide


• Introduction • Fuels from Fermentations: Ethanol • Hydrogen • Microbial Oils • Methane • Fuel from Chemical Conversion of Plant and Algal Oils: Biodiesel • Microbial Fuel Cells • Technical Resources

New Process Technology for Developing Low-Cost, Environmentally Safe Biofuels

Rising fuel prices have created a surge in the worldwide demand for biofuels made from plant and animal feedstocks. Filled with a wealth of illustrations, Biofuels Engineering Process Technology fully explains the concepts, systems, and technology now being used to produce biofuels on both an industrial and small scale.

Written by a team of leading biofuels experts, this lucid guide presents a complete introduction to biofuels and biorefining processes…state-of-the-art information on biofuels processed from fermentations of ethanol, hydrogen, microbial oils, and methane…new material on the production of biodiesel from plant and algal oils…and the use of microbial fuel cells to produce bioelectricity. Biofuels Engineering Process Technology takes readers step by step through:

  • The key concepts, systems, and technology of biofuels
  • A review of the basic concepts of fermentation pathways and kinetic modeling of bioreactors
  • Biofuels produced from fermentations of agricultural feedstocks and biomass-ethanol, hydrogen, microbial oils, and methane
  • Biodiesel fuels processed from the chemical conversion of microbial and plant oils
  • Bioelectricity produced from microbial fuel cells
  • The latest sustainable biorefinery concepts and methods

Inside This Cutting-Edge Biofuels Engineering Guide


• Introduction • Fuels from Fermentations: Ethanol • Hydrogen • Microbial Oils • Methane • Fuel from Chemical Conversion of Plant and Algal Oils: Biodiesel • Microbial Fuel Cells • Technical Resources.


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Seeds of Deception: Exposing Industry and Government Lies About the Safety of the Genetically Engineered Foods You're Eating

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Seeds of Deception: Exposing Industry and Government Lies About the Safety of the Genetically Engineered Foods You're Eating Info

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Without knowing it, Americans eat genetically modified (GM) food everyday. While the food and chemical industries claim that GMO food is safe, a considerable amount of evidence shows otherwise. In Seeds of Deception, Jeffrey Smith, a former executive with the leading independent laboratory testing for GM presence in foods, documents these serious health dangers and explains how corporate influence and government collusion have been used to cover them up.

The stories Smith presents read like a mystery novel. Scientists are offered bribes or threatened; evidence is stolen; data withheld or distorted. Government scientists who complain are stripped of responsibilities or fired. The FDA even withheld information from congress after a GM food supplement killed nearly a hundred people and permanently disabled thousands. While Smith was employed by the laboratory he was not allowed to speak on the health dangers or the cover-up. No longer bound by this agreement, Smith now reveals what he knows in this groundbreaking exposé.

Today, food companies sell GM foods that have not undergone safety studies. FDA scientists opposed this, but White House and industry pressure prevailed and the agency's final policy--co-authored by a former Monsanto attorney--denied the risks. The scientists' concerns were made public only after a lawsuit forced the agency to turn over internal documents.

Dan Glickman, former Secretary of Agriculture, describes the government's pro-biotech mindset: "You felt like you were almost an alien, disloyal, by trying to present an open-minded view. . . . So I pretty much spouted the rhetoric. . . . It was written into my speeches."

In Seeds of Deception Smith offers easy-to-understand descriptions of genetic engineering and explains why it can result in serious health problems. This well-documented, pivotal work will show you how to protect yourself and your family.

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Friday, 20 March 2015

Molecular Biology of The Cell: A Problems Approach

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Molecular Biology of The Cell: A Problems Approach La revue

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Molecular Biology of the Cell is the classic in-depth text reference in cell biology. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology..


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Essential Forensic Biology

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Essential Forensic Biology Info

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This book is an introduction to the application of biology in legal investigations. Fully revised and updated throughout, the second edition of this highly successful textbook offers an accessible overview to the essentials of the subject providing a balanced coverage of the range of organisms used as evidence in forensic investigations; invertebrates, vertebrates, plants and microbes.

The book provides an overview of the decay process and discusses the role of forensic indicators – human fluids and tissues, including blood cells, bloodstain pattern analysis, hair, teeth, bones, and wounds. It also examines the study of forensic biology in cases of suspicious death.

The coverage of molecular techniques has been expanded throughout with additional material on bioterrorism and wildlife forensics now included. The use of DNA and RNA for the identification of individuals and their personal characteristics is now covered along with a discussion of the ethical issues associated with the maintenance of DNA databases.

• Fully revised and updated new edition of this highly successful textbook.

• Includes self-assessment questions at the end of each chapter and case studies.

• Now in full colour throughout.

• Includes a supplementary website (www.wileyeurope.com/college/gunn) covering additional material and self-test questions to reinforce student understanding.


From the reviews of the first edition:

"The author does an excellent job of demonstrating how biological science can, and does, contribute to legal investigations…" THE QUARTERLY REVIEW OF BIOLOGY

"…a super book …not a book that will languish on library shelves. Buy it!" JOURNAL OF BIOLOGICAL EDUCATION

"…naturalists and biologists will find much of interest within these books…new light on the application of their own specialism..." THE NATURALIST

"Overall, I give it my highest recommendation. I was unable to find a single paragraph that was no fascinating, despite being sad or gruesome at times." E-STREAMS

This book is an introduction to the application of biology in legal investigations. Fully revised and updated throughout, the second edition of this highly successful textbook offers an accessible overview to the essentials of the subject providing a balanced coverage of the range of organisms used as evidence in forensic investigations; invertebrates, vertebrates, plants and microbes.

The book provides an overview of the decay process and discusses the role of forensic indicators – human fluids and tissues, including blood cells, bloodstain pattern analysis, hair, teeth, bones, and wounds. It also examines the study of forensic biology in cases of suspicious death.

The coverage of molecular techniques has been expanded throughout with additional material on bioterrorism and wildlife forensics now included. The use of DNA and RNA for the identification of individuals and their personal characteristics is now covered along with a discussion of the ethical issues associated with the maintenance of DNA databases.

• Fully revised and updated new edition of this highly successful textbook.

• Includes self-assessment questions at the end of each chapter and case studies.

• Now in full colour throughout.

• Includes a supplementary website (www.wileyeurope.com/college/gunn) covering additional material and self-test questions to reinforce student understanding.


From the reviews of the first edition:

"The author does an excellent job of demonstrating how biological science can, and does, contribute to legal investigations…" THE QUARTERLY REVIEW OF BIOLOGY

"…a super book …not a book that will languish on library shelves. Buy it!" JOURNAL OF BIOLOGICAL EDUCATION

"…naturalists and biologists will find much of interest within these books…new light on the application of their own specialism..." THE NATURALIST

"Overall, I give it my highest recommendation. I was unable to find a single paragraph that was no fascinating, despite being sad or gruesome at times." E-STREAMS

.


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Thursday, 19 March 2015

Dinoflagellates

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Dinoflagellates Info

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The book begins with a general introduction and a taxonomic description of the dinoflagellates both to acquaint those unfamiliar with this group of organisms and to set the tone for the rest of the volume. It then addresses the following topics: cell biology (cell cortex, nuclear structure, cell cycle and mitosis, sexual reproduction, cysts and unusual inclusions); biochemistry (physiology and biochemistry, blooms and toxins, and biorhythms); and genetics. In addition, a comprehensive chapter on cell culturing provides the reader with an understanding of the growth conditions and requirements of various dinoflagellates and a simple to follow listing of culture media, all expressed in similar units for ease of comparison. The volume closes with a chapter on evolution which evaluates many of the features of dinoflagellates discussed in the text in terms of evolutionary significance. We hope that this treatise will be of use to research workers and students in the area of dinoflagellate biology and in other areas of biology in which dinoflagellates may be used as a model system for studying various biological problems..


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Biotechnology and the Human Good

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Biotechnology and the Human Good La revue

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Some of humankind's greatest tools have been forged in the research laboratory. Who could argue that medical advances like antibiotics, blood transfusions, and pacemakers have not improved the quality of people's lives? But with each new technological breakthrough there comes an array of consequences, at once predicted and unpredictable, beneficial and hazardous.

Outcry over recent developments in the reproductive and genetic sciences has revealed deep fissures in society's perception of biotechnical progress. Many are concerned that reckless technological development, driven by consumerist impulses and greedy entrepreneurialism, has the potential to radically shift the human condition―and not for the greater good. Biotechnology and the Human Good builds a case for a stewardship deeply rooted in Judeo-Christian theism to responsibly interpret and assess new technologies in a way that answers this concern.

The authors jointly recognize humans not as autonomous beings but as ones accountable to each other, to the world they live in, and to God. They argue that to question and critique how fields like cybernetics, nanotechnology, and genetics might affect our future is not anti-science, anti-industry, or anti-progress, but rather a way to promote human flourishing, common sense, and good stewardship.

A synthetic work drawing on the thought of a physician, ethicists, and a theologian, Biotechnology and the Human Good reminds us that although technology is a powerful and often awe-inspiring tool, it is what lies in the heart and soul of who wields this tool that truly makes the difference in our world..


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Regenerative Biology and Medicine

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Regenerative Biology and Medicine Info

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Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering.

  • Highly Commended 2013 BMA Medical Book Award for Medicine
  • Includes coverage of skin, hair, teeth, cornea, and central neural tissues
  • Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems
  • Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals
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Wednesday, 18 March 2015

Lives of a Cell: Notes of a Biology Watcher

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Lives of a Cell: Notes of a Biology Watcher Info

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Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things.  Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine.  Lewis Thomas writes, "Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us.".


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Tuesday, 17 March 2015

The Antidote: Inside the World of New Pharma

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The Antidote: Inside the World of New Pharma Description

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This is the Moneyball of the pharma world, the story of one drug company’s quest to transform the pharmaceutical industry and a deeply revealing look into a world where breakneck capitalism meets life-saving medicine.

IN THE ANTIDOTE, Barry Werth draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking closeup of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits.

In 1989, the charismatic Joshua Boger left Merck, then America’s most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company’s tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex’s bold endurance and eventual success.

The 5 billion-a-year pharmaceutical business is America’s toughest and one of its most profitable. It’s riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world’s most regulated industry, matched only by nuclear power.

Werth captures the full scope of Vertex’s twentyfive- year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades..


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Transcend: Nine Steps to Living Well Forever

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Transcend: Nine Steps to Living Well Forever La revue

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In 2004, Ray Kurzweil and Terry Grossman, MD, published Fantastic Voyage: Live Long Enough to Live Forever. Their groundbreaking book marshaled thousands of scientific studies to make the case that new developments in medicine and technology will allow us to radically extend our life expectancies and slow down the aging process. Soon, our notion of what it means to be a 55-year-old will be as outdated as an eight-track tape player.

TRANSCEND: Nine Steps to Living Well Forever presents a practical, enjoyable program so that readers can live long enough (and remain healthy long enough) to take full advantage of the biotech and nanotech advances that have already begun and will be occurring at an accelerating pace during the years ahead. To help readers remember the nine key components of the program, Ray and Terry have arranged them into a mnemonic:

Talk with your doctor
Relaxation
Assessment
Nutrition
Supplementation
Calorie reduction
Exercise
New technologies
Detoxification

This easy-to-follow program will help readers transcend the boundaries of our genetic legacy and live long enough to live forever.

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Sunday, 15 March 2015

Molecular Biology of the Cell, Fourth Edition

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Molecular Biology of the Cell, Fourth Edition Info

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Molecular Biology of the Cell is the classic in-dept text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors..


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Friday, 13 March 2015

Medical Product Regulatory Affairs: Pharmaceuticals, Diagnostics, Medical Devices

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Written in a clear and concise style by an experienced author, this attractively-priced book covers regulatory affairs in all major global markets for pharmaceuticals and medical devices, making it the most comprehensive in its field.
Following a look at drug development, complete sections are devoted to national and EU regulatory issues, manufacturing license application and retention, and regulation in the USA. Other topics dealt with include CDER, CBER and marketing and manufacturing licenses, the ICH process and Good Laboratory/Clinical/Manufacturing Practices.
Everything pharmacologists, bioengineers, pharma engineers, students in pharmacy and those working in the pharmaceutical industry need to know about medical regulatory affairs..


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